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The Clinical Presentation of Endometriosis and Its Association to Current Surgical Staging

(1) Despite its high prevalence, the diagnostic delay of endometriosis is still estimated to be about 7 years. The objective of the present study is to understand the symptomatology of endometriosis in patients across various countries and to assess whether the severity of symptoms correlates with t...

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Autores principales: Ashkenazi, Matilda Shaked, Huseby, Ole Linvåg, Kroken, Gard, Trocha, Marcela, Henriksson, Aurora, Jasiak, Hanna, Cuartas, Karen, Loschiavo, Alessandra, Kuhn, Isabella, Støve, Dina, Grindahl, Hanna, Latour, Emilia, Melbø, Mathias, Holstad, Katrine, Kwiatkowski, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095514/
https://www.ncbi.nlm.nih.gov/pubmed/37048771
http://dx.doi.org/10.3390/jcm12072688
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author Ashkenazi, Matilda Shaked
Huseby, Ole Linvåg
Kroken, Gard
Trocha, Marcela
Henriksson, Aurora
Jasiak, Hanna
Cuartas, Karen
Loschiavo, Alessandra
Kuhn, Isabella
Støve, Dina
Grindahl, Hanna
Latour, Emilia
Melbø, Mathias
Holstad, Katrine
Kwiatkowski, Sebastian
author_facet Ashkenazi, Matilda Shaked
Huseby, Ole Linvåg
Kroken, Gard
Trocha, Marcela
Henriksson, Aurora
Jasiak, Hanna
Cuartas, Karen
Loschiavo, Alessandra
Kuhn, Isabella
Støve, Dina
Grindahl, Hanna
Latour, Emilia
Melbø, Mathias
Holstad, Katrine
Kwiatkowski, Sebastian
author_sort Ashkenazi, Matilda Shaked
collection PubMed
description (1) Despite its high prevalence, the diagnostic delay of endometriosis is still estimated to be about 7 years. The objective of the present study is to understand the symptomatology of endometriosis in patients across various countries and to assess whether the severity of symptoms correlates with the diagnosed stage of disease. (2) An international online survey collected self-reported responses from 2964 participants from 59 countries. Finalization of the questionnaire and its distribution was achieved by cooperation with various organizations and centers around the globe. (3) Chronic pain presentation remarkably increased between Stage 1 and 2 (16.2% and 32.2%, respectively). The prevalence of pain only around and during menstruation was negatively correlated to the stage, presenting with 15.4% and 6.9% in Stages 1 and 4, respectively. Atypical presentation of pain was most commonly reported in stage 4 (11.4%). Pain related solely to triggering factors was the most uncommon presentation of pain (3.2%). (4) Characteristics of pain and quality of life tend to differ depending on the reported stage of the endometriosis. Further research may allow a better stage estimation and identification of patients with alarming symptomatic presentation indicative of a progressive stage, even those that are not yet laparoscopically diagnosed.
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spelling pubmed-100955142023-04-13 The Clinical Presentation of Endometriosis and Its Association to Current Surgical Staging Ashkenazi, Matilda Shaked Huseby, Ole Linvåg Kroken, Gard Trocha, Marcela Henriksson, Aurora Jasiak, Hanna Cuartas, Karen Loschiavo, Alessandra Kuhn, Isabella Støve, Dina Grindahl, Hanna Latour, Emilia Melbø, Mathias Holstad, Katrine Kwiatkowski, Sebastian J Clin Med Article (1) Despite its high prevalence, the diagnostic delay of endometriosis is still estimated to be about 7 years. The objective of the present study is to understand the symptomatology of endometriosis in patients across various countries and to assess whether the severity of symptoms correlates with the diagnosed stage of disease. (2) An international online survey collected self-reported responses from 2964 participants from 59 countries. Finalization of the questionnaire and its distribution was achieved by cooperation with various organizations and centers around the globe. (3) Chronic pain presentation remarkably increased between Stage 1 and 2 (16.2% and 32.2%, respectively). The prevalence of pain only around and during menstruation was negatively correlated to the stage, presenting with 15.4% and 6.9% in Stages 1 and 4, respectively. Atypical presentation of pain was most commonly reported in stage 4 (11.4%). Pain related solely to triggering factors was the most uncommon presentation of pain (3.2%). (4) Characteristics of pain and quality of life tend to differ depending on the reported stage of the endometriosis. Further research may allow a better stage estimation and identification of patients with alarming symptomatic presentation indicative of a progressive stage, even those that are not yet laparoscopically diagnosed. MDPI 2023-04-04 /pmc/articles/PMC10095514/ /pubmed/37048771 http://dx.doi.org/10.3390/jcm12072688 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ashkenazi, Matilda Shaked
Huseby, Ole Linvåg
Kroken, Gard
Trocha, Marcela
Henriksson, Aurora
Jasiak, Hanna
Cuartas, Karen
Loschiavo, Alessandra
Kuhn, Isabella
Støve, Dina
Grindahl, Hanna
Latour, Emilia
Melbø, Mathias
Holstad, Katrine
Kwiatkowski, Sebastian
The Clinical Presentation of Endometriosis and Its Association to Current Surgical Staging
title The Clinical Presentation of Endometriosis and Its Association to Current Surgical Staging
title_full The Clinical Presentation of Endometriosis and Its Association to Current Surgical Staging
title_fullStr The Clinical Presentation of Endometriosis and Its Association to Current Surgical Staging
title_full_unstemmed The Clinical Presentation of Endometriosis and Its Association to Current Surgical Staging
title_short The Clinical Presentation of Endometriosis and Its Association to Current Surgical Staging
title_sort clinical presentation of endometriosis and its association to current surgical staging
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095514/
https://www.ncbi.nlm.nih.gov/pubmed/37048771
http://dx.doi.org/10.3390/jcm12072688
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