Transcriptomic Differences Underlying the Activin-A Induced Large Osteoclast Formation in Both Healthy Control and Fibrodysplasia Ossificans Progressiva Osteoclasts

Fibrodysplasia Ossificans Progressiva (FOP) is a very rare genetic disease characterized by progressive heterotopic ossification (HO) of soft tissues, leading to immobility and premature death. FOP is caused by a mutation in the Activin receptor Type 1 (ACVR1) gene, resulting in altered responsivene...

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Detalles Bibliográficos
Autores principales: Schoenmaker, Ton, Zwaak, Joy, Loos, Bruno G., Volckmann, Richard, Koster, Jan, Eekhoff, E. Marelise W., de Vries, Teun J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095588/
https://www.ncbi.nlm.nih.gov/pubmed/37047804
http://dx.doi.org/10.3390/ijms24076822

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