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The Anticancer Drug Daunomycin Directly Affects Gene Expression and DNA Structure

Daunomycin (DM), an anthracycline antibiotic, is frequently used to treat various cancers, but the direct effects of DM on gene expression and DNA structure are unclear. We used an in vitro cell-free system, optimized with spermine (SP), to study the effect of DM on gene expression. A bimodal effect...

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Detalles Bibliográficos
Autores principales:	Nishio, Takashi, Shimada, Yohji, Yoshikawa, Yuko, Kenmotsu, Takahiro, Schiessel, Helmut, Yoshikawa, Kenichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095590/ https://www.ncbi.nlm.nih.gov/pubmed/37047603 http://dx.doi.org/10.3390/ijms24076631

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