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Prevalence of High Aldosterone-Renin Ratio in Patients With Hypertension in Basrah

Background and aim: Aldosterone-renin ratio (ARR) is an important screening tool for the assessment of primary aldosteronism as a cause of secondary hypertension. This study aimed to measure the prevalence of patients with elevated ARR among samples of Iraqi patients with hypertension. Methods: A re...

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Autores principales: Zwain, Zeid, Nwayyir, Hussein A, Alidrisi, Haider A, Mansour, Abbas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095600/
https://www.ncbi.nlm.nih.gov/pubmed/37065379
http://dx.doi.org/10.7759/cureus.36085
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author Zwain, Zeid
Nwayyir, Hussein A
Alidrisi, Haider A
Mansour, Abbas A
author_facet Zwain, Zeid
Nwayyir, Hussein A
Alidrisi, Haider A
Mansour, Abbas A
author_sort Zwain, Zeid
collection PubMed
description Background and aim: Aldosterone-renin ratio (ARR) is an important screening tool for the assessment of primary aldosteronism as a cause of secondary hypertension. This study aimed to measure the prevalence of patients with elevated ARR among samples of Iraqi patients with hypertension. Methods: A retrospective study was conducted at Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC) in Basrah during the period of February 2020 to November 2021. We evaluated the records of patients with hypertension whom were screened for endocrine cause, and an ARR cut-off equal or more than 5.7 was considered elevated. Results: Of the total 150 patients enrolled, 39 (26%) of them had an elevated ARR. No statistically significant association for the elevated ARR with age, gender, BMI, duration of hypertension, systolic and diastolic blood pressure, pulse rate, and presence or absence of diabetes mellitus or lipid profile. Conclusion: High frequency of elevated ARR was seen in 26% of patients with hypertension. More studies need to be conducted in the future taking larger samples.
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spelling pubmed-100956002023-04-13 Prevalence of High Aldosterone-Renin Ratio in Patients With Hypertension in Basrah Zwain, Zeid Nwayyir, Hussein A Alidrisi, Haider A Mansour, Abbas A Cureus Endocrinology/Diabetes/Metabolism Background and aim: Aldosterone-renin ratio (ARR) is an important screening tool for the assessment of primary aldosteronism as a cause of secondary hypertension. This study aimed to measure the prevalence of patients with elevated ARR among samples of Iraqi patients with hypertension. Methods: A retrospective study was conducted at Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC) in Basrah during the period of February 2020 to November 2021. We evaluated the records of patients with hypertension whom were screened for endocrine cause, and an ARR cut-off equal or more than 5.7 was considered elevated. Results: Of the total 150 patients enrolled, 39 (26%) of them had an elevated ARR. No statistically significant association for the elevated ARR with age, gender, BMI, duration of hypertension, systolic and diastolic blood pressure, pulse rate, and presence or absence of diabetes mellitus or lipid profile. Conclusion: High frequency of elevated ARR was seen in 26% of patients with hypertension. More studies need to be conducted in the future taking larger samples. Cureus 2023-03-13 /pmc/articles/PMC10095600/ /pubmed/37065379 http://dx.doi.org/10.7759/cureus.36085 Text en Copyright © 2023, Zwain et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Zwain, Zeid
Nwayyir, Hussein A
Alidrisi, Haider A
Mansour, Abbas A
Prevalence of High Aldosterone-Renin Ratio in Patients With Hypertension in Basrah
title Prevalence of High Aldosterone-Renin Ratio in Patients With Hypertension in Basrah
title_full Prevalence of High Aldosterone-Renin Ratio in Patients With Hypertension in Basrah
title_fullStr Prevalence of High Aldosterone-Renin Ratio in Patients With Hypertension in Basrah
title_full_unstemmed Prevalence of High Aldosterone-Renin Ratio in Patients With Hypertension in Basrah
title_short Prevalence of High Aldosterone-Renin Ratio in Patients With Hypertension in Basrah
title_sort prevalence of high aldosterone-renin ratio in patients with hypertension in basrah
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095600/
https://www.ncbi.nlm.nih.gov/pubmed/37065379
http://dx.doi.org/10.7759/cureus.36085
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