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Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice

Malic Enzyme 1 (ME1) supports lipogenesis, cholesterol synthesis, and cellular redox potential by catalyzing the decarboxylation of L-malate to pyruvate, and the concomitant reduction of NADP to NADPH. We examined the contribution of ME1 to the development of obesity by provision of an obesogenic di...

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Detalles Bibliográficos
Autores principales:	Simmen, Frank A., Pabona, John Mark P., Al-Dwairi, Ahmed, Alhallak, Iad, Montales, Maria Theresa E., Simmen, Rosalia C. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095602/ https://www.ncbi.nlm.nih.gov/pubmed/37047583 http://dx.doi.org/10.3390/ijms24076613

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