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Ligand’s Partition to the Lipid Bilayer Should Be Accounted for When Estimating Their Affinity to Proteins

Ligand-protein interactions are usually studied in complex media that also contain lipids. This is particularly relevant for membrane proteins that are always associated with lipid bilayers, but also for water-soluble proteins studied in in vivo conditions. This work addresses the following two ques...

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Detalles Bibliográficos
Autores principales: Moreno, Maria João, Salvador, Armindo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095633/
https://www.ncbi.nlm.nih.gov/pubmed/37049898
http://dx.doi.org/10.3390/molecules28073136