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DNA Binding and Cleavage, Stopped-Flow Kinetic, Mechanistic, and Molecular Docking Studies of Cationic Ruthenium(II) Nitrosyl Complexes Containing “NS(4)” Core

HIGHLIGHTS: Theoretical studies were performed on [RuNOTSP](+), TSPH(2), and its anion TSP(2−) using the DFT/B3LYP method. Cationic complex [RuNOTSP](+) and TSPH(2) were investigated mechanistically for ctDNA interaction. Spontaneous ctDNA binding via a static mechanism with two steps was reported....

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Detalles Bibliográficos
Autores principales:	Shereef, Hadeer A., Moemen, Yasmine S., Elshami, Fawzia I., El-Nahas, Ahmed M., Shaban, Shaban Y., van Eldik, Rudi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095794/ https://www.ncbi.nlm.nih.gov/pubmed/37049792 http://dx.doi.org/10.3390/molecules28073028

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