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A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation
The light-induced reorientation of the cortical microtubule array in dark-grown Arabidopsis thaliana hypocotyl cells is a striking example of the dynamical plasticity of the microtubule cytoskeleton. A consensus model, based on katanin-mediated severing at microtubule crossovers, has been developed...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095967/ https://www.ncbi.nlm.nih.gov/pubmed/37077209 http://dx.doi.org/10.1017/qpb.2021.9 |
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author | Saltini, Marco Mulder, Bela M. |
author_facet | Saltini, Marco Mulder, Bela M. |
author_sort | Saltini, Marco |
collection | PubMed |
description | The light-induced reorientation of the cortical microtubule array in dark-grown Arabidopsis thaliana hypocotyl cells is a striking example of the dynamical plasticity of the microtubule cytoskeleton. A consensus model, based on katanin-mediated severing at microtubule crossovers, has been developed that successfully describes the onset of the observed switch between a transverse and longitudinal array orientation. However, we currently lack an understanding of why the newly populated longitudinal array direction remains stable for longer times and re-equilibration effects would tend to drive the system back to a mixed orientation state. Using both simulations and analytical calculations, we show that the assumption of a small orientation-dependent shift in microtubule dynamics is sufficient to explain the long-term lock-in of the longitudinal array orientation. Furthermore, we show that the natural alternative hypothesis that there is a selective advantage in severing longitudinal microtubules, is neither necessary nor sufficient to achieve cortical array reorientation, but is able to accelerate this process significantly. |
format | Online Article Text |
id | pubmed-10095967 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-100959672023-04-18 A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation Saltini, Marco Mulder, Bela M. Quant Plant Biol Original Research Article The light-induced reorientation of the cortical microtubule array in dark-grown Arabidopsis thaliana hypocotyl cells is a striking example of the dynamical plasticity of the microtubule cytoskeleton. A consensus model, based on katanin-mediated severing at microtubule crossovers, has been developed that successfully describes the onset of the observed switch between a transverse and longitudinal array orientation. However, we currently lack an understanding of why the newly populated longitudinal array direction remains stable for longer times and re-equilibration effects would tend to drive the system back to a mixed orientation state. Using both simulations and analytical calculations, we show that the assumption of a small orientation-dependent shift in microtubule dynamics is sufficient to explain the long-term lock-in of the longitudinal array orientation. Furthermore, we show that the natural alternative hypothesis that there is a selective advantage in severing longitudinal microtubules, is neither necessary nor sufficient to achieve cortical array reorientation, but is able to accelerate this process significantly. Cambridge University Press 2021-05-18 /pmc/articles/PMC10095967/ /pubmed/37077209 http://dx.doi.org/10.1017/qpb.2021.9 Text en © The Author(s), 2021. Published by Cambridge University Press in association with The John Innes Centre 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited |
spellingShingle | Original Research Article Saltini, Marco Mulder, Bela M. A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
title | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
title_full | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
title_fullStr | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
title_full_unstemmed | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
title_short | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
title_sort | plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095967/ https://www.ncbi.nlm.nih.gov/pubmed/37077209 http://dx.doi.org/10.1017/qpb.2021.9 |
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