BET Bromodomain Inhibitors: Novel Design Strategies and Therapeutic Applications

The mammalian bromodomain and extra-terminal domain (BET) family of proteins consists of four conserved members (Brd2, Brd3, Brd4, and Brdt) that regulate numerous cancer-related and immunity-associated genes. They are epigenetic readers of histone acetylation with broad specificity. BET proteins ar...

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Detalles Bibliográficos
Autores principales: To, Kenneth K. W., Xing, Enming, Larue, Ross C., Li, Pui-Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096006/
https://www.ncbi.nlm.nih.gov/pubmed/37049806
http://dx.doi.org/10.3390/molecules28073043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096006/
https://www.ncbi.nlm.nih.gov/pubmed/37049806
http://dx.doi.org/10.3390/molecules28073043

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