New 6′-Amino-5′-cyano-2-oxo-1,2-dihydro-1′H-spiro[indole-3,4′-pyridine]-3′-carboxamides: Synthesis, Reactions, Molecular Docking Studies and Biological Activity

The purpose of this work was to prepare new isatin- and monothiomalondiamide-based indole derivatives, as well as to study the properties of the new compounds. The four-component reaction of 5-R-isatins (R = H, CH(3)), malononitrile, monothiomalonamide (3-amino-3-thioxo- propanamide) and triethylami...

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Detalles Bibliográficos
Autores principales: Dotsenko, Victor V., Jassim, Nawras T., Temerdashev, Azamat Z., Abdul-Hussein, Zainab R., Aksenov, Nicolai A., Aksenova, Inna V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096136/
https://www.ncbi.nlm.nih.gov/pubmed/37049923
http://dx.doi.org/10.3390/molecules28073161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096136/
https://www.ncbi.nlm.nih.gov/pubmed/37049923
http://dx.doi.org/10.3390/molecules28073161

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