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Predicting activatory and inhibitory drug–target interactions based on structural compound representations and genetically perturbed transcriptomes
A computational approach to identifying drug–target interactions (DTIs) is a credible strategy for accelerating drug development and understanding the mechanisms of action of small molecules. However, current methods to predict DTIs have mainly focused on identifying simple interactions, requiring f...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096289/ https://www.ncbi.nlm.nih.gov/pubmed/37043429 http://dx.doi.org/10.1371/journal.pone.0282042 |