The Protective Effects of Goitrin on LPS-Induced Septic Shock in C57BL/6J Mice via Caspase-11 Non-Canonical Inflammasome Inhibition

Septic shock is defined as a subset of sepsis, which is associated with a considerably high mortality risk. The caspase-11 non-canonical inflammasome is sensed and activated by intracellular lipopolysaccharide (LPS) leading to pyroptosis, it plays a critical role in septic shock. However, there are...

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Detalles Bibliográficos
Autores principales: Ruan, Deqing, Yang, Jingyi, Luo, Qianfei, Shi, Yanhong, Ding, Lili, Wang, Zhengtao, Wang, Rui, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096381/
https://www.ncbi.nlm.nih.gov/pubmed/37049646
http://dx.doi.org/10.3390/molecules28072883

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