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Synthesis of Tetrasubstituted Nitroalkenes and Preliminary Studies of Their Enantioselective Organocatalytic Reduction

Starting from commercially available ketones, a reproducible and reliable strategy for the synthesis of tetrasubstituted nitroalkenes was successfully developed, using a two-step procedure; the HWE olefination of the ketone to form the corresponding α,β-unsaturated esters is followed by a nitration...

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Detalles Bibliográficos
Autores principales: González, Patricia Camarero, Rossi, Sergio, Sanz, Miguel, Vasile, Francesca, Benaglia, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096420/
https://www.ncbi.nlm.nih.gov/pubmed/37049919
http://dx.doi.org/10.3390/molecules28073156