Localized immune surveillance of primary melanoma in the skin deciphered through executable modeling

While skin is a site of active immune surveillance, primary melanomas often escape detection. Here, we have developed an in silico model to determine the local cross-talk between melanomas and Langerhans cells (LCs), the primary antigen-presenting cells at the site of melanoma development. The model...

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Detalles Bibliográficos
Autores principales: Howell, Rowan, Davies, James, Clarke, Matthew A., Appios, Anna, Mesquita, Inês, Jayal, Yashoda, Ringham-Terry, Ben, Boned Del Rio, Isabel, Fisher, Jasmin, Bennett, Clare L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096595/
https://www.ncbi.nlm.nih.gov/pubmed/37043573
http://dx.doi.org/10.1126/sciadv.add1992

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