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Indirect Calorimetry to Measure Metabolic Rate and Energy Expenditure in Psychiatric Populations: A Systematic Review
Psychiatric and metabolic disorders are highly comorbid and the relationship between these disorders is bidirectional. The mechanisms underlying the association between psychiatric and metabolic disorders are presently unclear, which warrants investigation into the dynamics of the interplay between...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096641/ https://www.ncbi.nlm.nih.gov/pubmed/37049526 http://dx.doi.org/10.3390/nu15071686 |
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author | Di Vincenzo, Joshua Daniel O’Brien, Liam Jacobs, Ira Jawad, Muhammad Youshay Ceban, Felicia Meshkat, Shakila Gill, Hartej Tabassum, Aniqa Phan, Lee Badulescu, Sebastian Rosenblat, Joshua Daniel McIntyre, Roger S. Mansur, Rodrigo B. |
author_facet | Di Vincenzo, Joshua Daniel O’Brien, Liam Jacobs, Ira Jawad, Muhammad Youshay Ceban, Felicia Meshkat, Shakila Gill, Hartej Tabassum, Aniqa Phan, Lee Badulescu, Sebastian Rosenblat, Joshua Daniel McIntyre, Roger S. Mansur, Rodrigo B. |
author_sort | Di Vincenzo, Joshua Daniel |
collection | PubMed |
description | Psychiatric and metabolic disorders are highly comorbid and the relationship between these disorders is bidirectional. The mechanisms underlying the association between psychiatric and metabolic disorders are presently unclear, which warrants investigation into the dynamics of the interplay between metabolism, substrate utilization, and energy expenditure in psychiatric populations, and how these constructs compare to those in healthy controls. Indirect calorimetry (IC) methods are a reliable, minimally invasive means for assessing metabolic rate and substrate utilization in humans. This review synthesizes the extant literature on the use of IC on resting metabolism in psychiatric populations to investigate the interaction between psychiatric and metabolic functioning. Consistently, resting energy expenditures and/or substrate utilization values were significantly different between psychiatric and healthy populations in the studies contained in this review. Furthermore, resting energy expenditure values were systematically overestimated when derived from predictive equations, compared to when measured by IC, in psychiatric populations. High heterogeneity between study populations (e.g., differing diagnoses and drug regimens) and methodologies (e.g., differing posture, time of day, and fasting status at measurement) impeded the synthesis of results. Standardized IC protocols would benefit this line of research by enabling meta-analyses, revealing trends within and between different psychiatric disorders. |
format | Online Article Text |
id | pubmed-10096641 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100966412023-04-13 Indirect Calorimetry to Measure Metabolic Rate and Energy Expenditure in Psychiatric Populations: A Systematic Review Di Vincenzo, Joshua Daniel O’Brien, Liam Jacobs, Ira Jawad, Muhammad Youshay Ceban, Felicia Meshkat, Shakila Gill, Hartej Tabassum, Aniqa Phan, Lee Badulescu, Sebastian Rosenblat, Joshua Daniel McIntyre, Roger S. Mansur, Rodrigo B. Nutrients Review Psychiatric and metabolic disorders are highly comorbid and the relationship between these disorders is bidirectional. The mechanisms underlying the association between psychiatric and metabolic disorders are presently unclear, which warrants investigation into the dynamics of the interplay between metabolism, substrate utilization, and energy expenditure in psychiatric populations, and how these constructs compare to those in healthy controls. Indirect calorimetry (IC) methods are a reliable, minimally invasive means for assessing metabolic rate and substrate utilization in humans. This review synthesizes the extant literature on the use of IC on resting metabolism in psychiatric populations to investigate the interaction between psychiatric and metabolic functioning. Consistently, resting energy expenditures and/or substrate utilization values were significantly different between psychiatric and healthy populations in the studies contained in this review. Furthermore, resting energy expenditure values were systematically overestimated when derived from predictive equations, compared to when measured by IC, in psychiatric populations. High heterogeneity between study populations (e.g., differing diagnoses and drug regimens) and methodologies (e.g., differing posture, time of day, and fasting status at measurement) impeded the synthesis of results. Standardized IC protocols would benefit this line of research by enabling meta-analyses, revealing trends within and between different psychiatric disorders. MDPI 2023-03-30 /pmc/articles/PMC10096641/ /pubmed/37049526 http://dx.doi.org/10.3390/nu15071686 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Di Vincenzo, Joshua Daniel O’Brien, Liam Jacobs, Ira Jawad, Muhammad Youshay Ceban, Felicia Meshkat, Shakila Gill, Hartej Tabassum, Aniqa Phan, Lee Badulescu, Sebastian Rosenblat, Joshua Daniel McIntyre, Roger S. Mansur, Rodrigo B. Indirect Calorimetry to Measure Metabolic Rate and Energy Expenditure in Psychiatric Populations: A Systematic Review |
title | Indirect Calorimetry to Measure Metabolic Rate and Energy Expenditure in Psychiatric Populations: A Systematic Review |
title_full | Indirect Calorimetry to Measure Metabolic Rate and Energy Expenditure in Psychiatric Populations: A Systematic Review |
title_fullStr | Indirect Calorimetry to Measure Metabolic Rate and Energy Expenditure in Psychiatric Populations: A Systematic Review |
title_full_unstemmed | Indirect Calorimetry to Measure Metabolic Rate and Energy Expenditure in Psychiatric Populations: A Systematic Review |
title_short | Indirect Calorimetry to Measure Metabolic Rate and Energy Expenditure in Psychiatric Populations: A Systematic Review |
title_sort | indirect calorimetry to measure metabolic rate and energy expenditure in psychiatric populations: a systematic review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096641/ https://www.ncbi.nlm.nih.gov/pubmed/37049526 http://dx.doi.org/10.3390/nu15071686 |
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