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Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department

The controlling nutritional status (CONUT) score represents poor nutritional status and has been identified as an indicator of adverse outcomes. Our aim was to evaluate the prognostic role of the CONUT score on in-hospital outcomes in an Internal Medicine Department. This is a retrospective study an...

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Autores principales: Miano, Nicoletta, Di Marco, Maurizio, Alaimo, Salvatore, Coppolino, Giuseppe, L’Episcopo, Giuseppe, Leggio, Stefano, Scicali, Roberto, Piro, Salvatore, Purrello, Francesco, Di Pino, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096657/
https://www.ncbi.nlm.nih.gov/pubmed/37049392
http://dx.doi.org/10.3390/nu15071554
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author Miano, Nicoletta
Di Marco, Maurizio
Alaimo, Salvatore
Coppolino, Giuseppe
L’Episcopo, Giuseppe
Leggio, Stefano
Scicali, Roberto
Piro, Salvatore
Purrello, Francesco
Di Pino, Antonino
author_facet Miano, Nicoletta
Di Marco, Maurizio
Alaimo, Salvatore
Coppolino, Giuseppe
L’Episcopo, Giuseppe
Leggio, Stefano
Scicali, Roberto
Piro, Salvatore
Purrello, Francesco
Di Pino, Antonino
author_sort Miano, Nicoletta
collection PubMed
description The controlling nutritional status (CONUT) score represents poor nutritional status and has been identified as an indicator of adverse outcomes. Our aim was to evaluate the prognostic role of the CONUT score on in-hospital outcomes in an Internal Medicine Department. This is a retrospective study analyzing data from 369 patients, divided into four groups based on the CONUT score: normal (0–1), mild–high (2–4), moderate–high (5–8), and marked high (9–12). In-hospital all-cause mortality increased from normal to marked high CONUT score group (2.2% vs. 3.6% vs. 13.4% vs. 15.3%, p < 0.009). Furthermore, a higher CONUT score was linked to a longer length of hospital stay (LOS) (9.48 ± 6.22 vs. 11.09 ± 7.11 vs. 12.45 ± 7.88 vs. 13.10 ± 8.12, p < 0.013) and an increased prevalence of sepsis. The excess risk of a high CONUT score relative to a low CONUT score remained significant after adjusting for confounders (all-cause mortality: OR: 3.3, 95% CI: 1.1–9.7, p < 0.02; sepsis: OR: 2.7, 95% CI: 1.5–4.9, p < 0.01; LOS: OR: 2.1, 95% CI: 1.2–3.9, p < 0.007). The present study demonstrated that an increased CONUT score is related to a higher risk of short-term in-hospital death and complications.
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spelling pubmed-100966572023-04-13 Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department Miano, Nicoletta Di Marco, Maurizio Alaimo, Salvatore Coppolino, Giuseppe L’Episcopo, Giuseppe Leggio, Stefano Scicali, Roberto Piro, Salvatore Purrello, Francesco Di Pino, Antonino Nutrients Article The controlling nutritional status (CONUT) score represents poor nutritional status and has been identified as an indicator of adverse outcomes. Our aim was to evaluate the prognostic role of the CONUT score on in-hospital outcomes in an Internal Medicine Department. This is a retrospective study analyzing data from 369 patients, divided into four groups based on the CONUT score: normal (0–1), mild–high (2–4), moderate–high (5–8), and marked high (9–12). In-hospital all-cause mortality increased from normal to marked high CONUT score group (2.2% vs. 3.6% vs. 13.4% vs. 15.3%, p < 0.009). Furthermore, a higher CONUT score was linked to a longer length of hospital stay (LOS) (9.48 ± 6.22 vs. 11.09 ± 7.11 vs. 12.45 ± 7.88 vs. 13.10 ± 8.12, p < 0.013) and an increased prevalence of sepsis. The excess risk of a high CONUT score relative to a low CONUT score remained significant after adjusting for confounders (all-cause mortality: OR: 3.3, 95% CI: 1.1–9.7, p < 0.02; sepsis: OR: 2.7, 95% CI: 1.5–4.9, p < 0.01; LOS: OR: 2.1, 95% CI: 1.2–3.9, p < 0.007). The present study demonstrated that an increased CONUT score is related to a higher risk of short-term in-hospital death and complications. MDPI 2023-03-23 /pmc/articles/PMC10096657/ /pubmed/37049392 http://dx.doi.org/10.3390/nu15071554 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Miano, Nicoletta
Di Marco, Maurizio
Alaimo, Salvatore
Coppolino, Giuseppe
L’Episcopo, Giuseppe
Leggio, Stefano
Scicali, Roberto
Piro, Salvatore
Purrello, Francesco
Di Pino, Antonino
Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department
title Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department
title_full Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department
title_fullStr Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department
title_full_unstemmed Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department
title_short Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department
title_sort controlling nutritional status (conut) score as a potential prognostic indicator of in-hospital mortality, sepsis and length of stay in an internal medicine department
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096657/
https://www.ncbi.nlm.nih.gov/pubmed/37049392
http://dx.doi.org/10.3390/nu15071554
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