Cargando…
Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department
The controlling nutritional status (CONUT) score represents poor nutritional status and has been identified as an indicator of adverse outcomes. Our aim was to evaluate the prognostic role of the CONUT score on in-hospital outcomes in an Internal Medicine Department. This is a retrospective study an...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096657/ https://www.ncbi.nlm.nih.gov/pubmed/37049392 http://dx.doi.org/10.3390/nu15071554 |
_version_ | 1785024389837750272 |
---|---|
author | Miano, Nicoletta Di Marco, Maurizio Alaimo, Salvatore Coppolino, Giuseppe L’Episcopo, Giuseppe Leggio, Stefano Scicali, Roberto Piro, Salvatore Purrello, Francesco Di Pino, Antonino |
author_facet | Miano, Nicoletta Di Marco, Maurizio Alaimo, Salvatore Coppolino, Giuseppe L’Episcopo, Giuseppe Leggio, Stefano Scicali, Roberto Piro, Salvatore Purrello, Francesco Di Pino, Antonino |
author_sort | Miano, Nicoletta |
collection | PubMed |
description | The controlling nutritional status (CONUT) score represents poor nutritional status and has been identified as an indicator of adverse outcomes. Our aim was to evaluate the prognostic role of the CONUT score on in-hospital outcomes in an Internal Medicine Department. This is a retrospective study analyzing data from 369 patients, divided into four groups based on the CONUT score: normal (0–1), mild–high (2–4), moderate–high (5–8), and marked high (9–12). In-hospital all-cause mortality increased from normal to marked high CONUT score group (2.2% vs. 3.6% vs. 13.4% vs. 15.3%, p < 0.009). Furthermore, a higher CONUT score was linked to a longer length of hospital stay (LOS) (9.48 ± 6.22 vs. 11.09 ± 7.11 vs. 12.45 ± 7.88 vs. 13.10 ± 8.12, p < 0.013) and an increased prevalence of sepsis. The excess risk of a high CONUT score relative to a low CONUT score remained significant after adjusting for confounders (all-cause mortality: OR: 3.3, 95% CI: 1.1–9.7, p < 0.02; sepsis: OR: 2.7, 95% CI: 1.5–4.9, p < 0.01; LOS: OR: 2.1, 95% CI: 1.2–3.9, p < 0.007). The present study demonstrated that an increased CONUT score is related to a higher risk of short-term in-hospital death and complications. |
format | Online Article Text |
id | pubmed-10096657 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100966572023-04-13 Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department Miano, Nicoletta Di Marco, Maurizio Alaimo, Salvatore Coppolino, Giuseppe L’Episcopo, Giuseppe Leggio, Stefano Scicali, Roberto Piro, Salvatore Purrello, Francesco Di Pino, Antonino Nutrients Article The controlling nutritional status (CONUT) score represents poor nutritional status and has been identified as an indicator of adverse outcomes. Our aim was to evaluate the prognostic role of the CONUT score on in-hospital outcomes in an Internal Medicine Department. This is a retrospective study analyzing data from 369 patients, divided into four groups based on the CONUT score: normal (0–1), mild–high (2–4), moderate–high (5–8), and marked high (9–12). In-hospital all-cause mortality increased from normal to marked high CONUT score group (2.2% vs. 3.6% vs. 13.4% vs. 15.3%, p < 0.009). Furthermore, a higher CONUT score was linked to a longer length of hospital stay (LOS) (9.48 ± 6.22 vs. 11.09 ± 7.11 vs. 12.45 ± 7.88 vs. 13.10 ± 8.12, p < 0.013) and an increased prevalence of sepsis. The excess risk of a high CONUT score relative to a low CONUT score remained significant after adjusting for confounders (all-cause mortality: OR: 3.3, 95% CI: 1.1–9.7, p < 0.02; sepsis: OR: 2.7, 95% CI: 1.5–4.9, p < 0.01; LOS: OR: 2.1, 95% CI: 1.2–3.9, p < 0.007). The present study demonstrated that an increased CONUT score is related to a higher risk of short-term in-hospital death and complications. MDPI 2023-03-23 /pmc/articles/PMC10096657/ /pubmed/37049392 http://dx.doi.org/10.3390/nu15071554 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Miano, Nicoletta Di Marco, Maurizio Alaimo, Salvatore Coppolino, Giuseppe L’Episcopo, Giuseppe Leggio, Stefano Scicali, Roberto Piro, Salvatore Purrello, Francesco Di Pino, Antonino Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department |
title | Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department |
title_full | Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department |
title_fullStr | Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department |
title_full_unstemmed | Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department |
title_short | Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department |
title_sort | controlling nutritional status (conut) score as a potential prognostic indicator of in-hospital mortality, sepsis and length of stay in an internal medicine department |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096657/ https://www.ncbi.nlm.nih.gov/pubmed/37049392 http://dx.doi.org/10.3390/nu15071554 |
work_keys_str_mv | AT mianonicoletta controllingnutritionalstatusconutscoreasapotentialprognosticindicatorofinhospitalmortalitysepsisandlengthofstayinaninternalmedicinedepartment AT dimarcomaurizio controllingnutritionalstatusconutscoreasapotentialprognosticindicatorofinhospitalmortalitysepsisandlengthofstayinaninternalmedicinedepartment AT alaimosalvatore controllingnutritionalstatusconutscoreasapotentialprognosticindicatorofinhospitalmortalitysepsisandlengthofstayinaninternalmedicinedepartment AT coppolinogiuseppe controllingnutritionalstatusconutscoreasapotentialprognosticindicatorofinhospitalmortalitysepsisandlengthofstayinaninternalmedicinedepartment AT lepiscopogiuseppe controllingnutritionalstatusconutscoreasapotentialprognosticindicatorofinhospitalmortalitysepsisandlengthofstayinaninternalmedicinedepartment AT leggiostefano controllingnutritionalstatusconutscoreasapotentialprognosticindicatorofinhospitalmortalitysepsisandlengthofstayinaninternalmedicinedepartment AT scicaliroberto controllingnutritionalstatusconutscoreasapotentialprognosticindicatorofinhospitalmortalitysepsisandlengthofstayinaninternalmedicinedepartment AT pirosalvatore controllingnutritionalstatusconutscoreasapotentialprognosticindicatorofinhospitalmortalitysepsisandlengthofstayinaninternalmedicinedepartment AT purrellofrancesco controllingnutritionalstatusconutscoreasapotentialprognosticindicatorofinhospitalmortalitysepsisandlengthofstayinaninternalmedicinedepartment AT dipinoantonino controllingnutritionalstatusconutscoreasapotentialprognosticindicatorofinhospitalmortalitysepsisandlengthofstayinaninternalmedicinedepartment |