Identification of Flavone Derivative Displaying a 4′-Aminophenoxy Moiety as Potential Selective Anticancer Agent in NSCLC Tumor Cells

Five heterocyclic derivatives were synthesized by functionalization of a flavone nucleus with an aminophenoxy moiety. Their cytotoxicity was investigated in vitro in two models of human non-small cell lung cancer (NSCLC) cells (A549 and NCI-H1975) by using MTT assay and the results compared to those...

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Detalles Bibliográficos
Autores principales: Mobbili, Giovanna, Romaldi, Brenda, Sabbatini, Giulia, Amici, Adolfo, Marcaccio, Massimo, Galeazzi, Roberta, Laudadio, Emiliano, Armeni, Tatiana, Minnelli, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096842/
https://www.ncbi.nlm.nih.gov/pubmed/37050002
http://dx.doi.org/10.3390/molecules28073239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096842/
https://www.ncbi.nlm.nih.gov/pubmed/37050002
http://dx.doi.org/10.3390/molecules28073239

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