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Nanotechnology Promoting the Development of Products from the Biodiversity of the Asteraceae Family

Biodiversity is a hallmark of the Asteraceae family. Several species are known for their pharmacological potential. The search for new substances has permeated the chemistry of natural products for years. However, the development of a final product is still a challenge. Plant extracts have physicoch...

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Autores principales: Yien, Raíssa Mara Kao, Matos, Ana Paula dos Santos, Gomes, Anne Caroline Candido, Garófalo, Denise de Abreu, Santos-Oliveira, Ralph, Simas, Naomi Kato, Ricci-Júnior, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096939/
https://www.ncbi.nlm.nih.gov/pubmed/37049452
http://dx.doi.org/10.3390/nu15071610
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author Yien, Raíssa Mara Kao
Matos, Ana Paula dos Santos
Gomes, Anne Caroline Candido
Garófalo, Denise de Abreu
Santos-Oliveira, Ralph
Simas, Naomi Kato
Ricci-Júnior, Eduardo
author_facet Yien, Raíssa Mara Kao
Matos, Ana Paula dos Santos
Gomes, Anne Caroline Candido
Garófalo, Denise de Abreu
Santos-Oliveira, Ralph
Simas, Naomi Kato
Ricci-Júnior, Eduardo
author_sort Yien, Raíssa Mara Kao
collection PubMed
description Biodiversity is a hallmark of the Asteraceae family. Several species are known for their pharmacological potential. The search for new substances has permeated the chemistry of natural products for years. However, the development of a final product is still a challenge. Plant extracts have physicochemical characteristics that sometimes hinder administration, requiring a formulation. In this context, nanotechnology emerges as a tool to improve the pharmacokinetic parameters of several pharmacologically active substances. Nanoemulsions, liposomes, and nanoparticles are used to carry the active ingredients and thus improve therapeutic action, especially for substances with solubility and absorption problems. This paper aimed at compiling all the studies that used nanotechnology to develop formulations from species of the Asteraceae family from 2010 to 2021 in a literature review. The search showed that nanoemulsions are the most developed formulation associated with essential oils. The use of nanotechnology promoted an improvement in the pharmacokinetic parameters of active substances.
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spelling pubmed-100969392023-04-13 Nanotechnology Promoting the Development of Products from the Biodiversity of the Asteraceae Family Yien, Raíssa Mara Kao Matos, Ana Paula dos Santos Gomes, Anne Caroline Candido Garófalo, Denise de Abreu Santos-Oliveira, Ralph Simas, Naomi Kato Ricci-Júnior, Eduardo Nutrients Review Biodiversity is a hallmark of the Asteraceae family. Several species are known for their pharmacological potential. The search for new substances has permeated the chemistry of natural products for years. However, the development of a final product is still a challenge. Plant extracts have physicochemical characteristics that sometimes hinder administration, requiring a formulation. In this context, nanotechnology emerges as a tool to improve the pharmacokinetic parameters of several pharmacologically active substances. Nanoemulsions, liposomes, and nanoparticles are used to carry the active ingredients and thus improve therapeutic action, especially for substances with solubility and absorption problems. This paper aimed at compiling all the studies that used nanotechnology to develop formulations from species of the Asteraceae family from 2010 to 2021 in a literature review. The search showed that nanoemulsions are the most developed formulation associated with essential oils. The use of nanotechnology promoted an improvement in the pharmacokinetic parameters of active substances. MDPI 2023-03-26 /pmc/articles/PMC10096939/ /pubmed/37049452 http://dx.doi.org/10.3390/nu15071610 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yien, Raíssa Mara Kao
Matos, Ana Paula dos Santos
Gomes, Anne Caroline Candido
Garófalo, Denise de Abreu
Santos-Oliveira, Ralph
Simas, Naomi Kato
Ricci-Júnior, Eduardo
Nanotechnology Promoting the Development of Products from the Biodiversity of the Asteraceae Family
title Nanotechnology Promoting the Development of Products from the Biodiversity of the Asteraceae Family
title_full Nanotechnology Promoting the Development of Products from the Biodiversity of the Asteraceae Family
title_fullStr Nanotechnology Promoting the Development of Products from the Biodiversity of the Asteraceae Family
title_full_unstemmed Nanotechnology Promoting the Development of Products from the Biodiversity of the Asteraceae Family
title_short Nanotechnology Promoting the Development of Products from the Biodiversity of the Asteraceae Family
title_sort nanotechnology promoting the development of products from the biodiversity of the asteraceae family
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096939/
https://www.ncbi.nlm.nih.gov/pubmed/37049452
http://dx.doi.org/10.3390/nu15071610
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