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Synthesis of 5-Fluorouracil Polymer Conjugate and (19)F NMR Analysis of Drug Release for MRI Monitoring
To monitor the release of fluorinated drugs from polymeric carriers, a novel (19)F MRI enzyme-responsive contrast agent was developed and tested. This contrast agent was prepared by conjugation of 5-fluorouracil (5-FU) to hyperbranched poly(N,N-dimethylacrylamide) (HB-PDMA) via an enzyme-degradable...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097235/ https://www.ncbi.nlm.nih.gov/pubmed/37050392 http://dx.doi.org/10.3390/polym15071778 |