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Reassessment of weak parent-of-origin expression bias shows it rarely exists outside of known imprinted regions

In mouse and human, genes subjected to genomic imprinting have been shown to function in development, behavior, and post-natal adaptations. Failure to correctly imprint genes in human is associated with developmental syndromes, adaptive, and metabolic disorders during life as well as numerous forms...

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Detalles Bibliográficos
Autores principales: Edwards, Carol A, Watkinson, William MD, Telerman, Stephanie B, Hulsmann, Lisa C, Hamilton, Russell S, Ferguson-Smith, Anne C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097420/
https://www.ncbi.nlm.nih.gov/pubmed/36916665
http://dx.doi.org/10.7554/eLife.83364