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Identification of phenotypically, functionally, and anatomically distinct stromal niche populations in human bone marrow based on single-cell RNA sequencing

Hematopoiesis is regulated by the bone marrow (BM) stroma. However, cellular identities and functions of the different BM stromal elements in humans remain poorly defined. Based on single-cell RNA sequencing (scRNAseq), we systematically characterized the human non-hematopoietic BM stromal compartme...

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Detalles Bibliográficos
Autores principales: Li, Hongzhe, Bräunig, Sandro, Dhapolar, Parashar, Karlsson, Göran, Lang, Stefan, Scheding, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097421/
https://www.ncbi.nlm.nih.gov/pubmed/36876630
http://dx.doi.org/10.7554/eLife.81656