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Fucoxanthin protects retinal ganglion cells and promotes parkin-mediated mitophagy against glutamate excitotoxicity

To clarify whether fucoxanthin plays a protective role and regulates parkin-mediated mitophagy on retinal ganglion cells (RGCs) against glutamate excitotoxicity. METHODS: The excitotoxicity model of primary RGCs was carried out with glutamate. Mitochondrial membrane potential was measured by JC-1 ki...

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Detalles Bibliográficos
Autores principales: Lian, Wei, Hu, Xinxin, Zhang, Juntao, Wu, Yufei, Zhao, Na, Ma, Haixia, He, Hengqian, Lu, Qinkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097491/
https://www.ncbi.nlm.nih.gov/pubmed/37096783
http://dx.doi.org/10.1097/WNR.0000000000001902