Associate toxin-antitoxin with CRISPR-Cas to kill multidrug-resistant pathogens

CreTA, CRISPR-regulated toxin-antitoxin (TA), safeguards CRISPR-Cas immune systems by inducing cell dormancy/death upon their inactivation. Here, we characterize a bacterial CreTA associating with the I-F CRISPR-Cas in Acinetobacter. CreT is a distinct bactericidal small RNA likely targeting several...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Shu, Xian, Zhao, Huiwei, Xue, Qiong, Liu, Chao, Wu, Aici, Cheng, Feiyue, Wang, Lingyun, Zhang, Yihan, Feng, Jie, Wu, Nannan, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097628/
https://www.ncbi.nlm.nih.gov/pubmed/37045931
http://dx.doi.org/10.1038/s41467-023-37789-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097628/
https://www.ncbi.nlm.nih.gov/pubmed/37045931
http://dx.doi.org/10.1038/s41467-023-37789-y

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