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Associate toxin-antitoxin with CRISPR-Cas to kill multidrug-resistant pathogens

CreTA, CRISPR-regulated toxin-antitoxin (TA), safeguards CRISPR-Cas immune systems by inducing cell dormancy/death upon their inactivation. Here, we characterize a bacterial CreTA associating with the I-F CRISPR-Cas in Acinetobacter. CreT is a distinct bactericidal small RNA likely targeting several...

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Detalles Bibliográficos
Autores principales:	Wang, Rui, Shu, Xian, Zhao, Huiwei, Xue, Qiong, Liu, Chao, Wu, Aici, Cheng, Feiyue, Wang, Lingyun, Zhang, Yihan, Feng, Jie, Wu, Nannan, Li, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097628/ https://www.ncbi.nlm.nih.gov/pubmed/37045931 http://dx.doi.org/10.1038/s41467-023-37789-y

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