Mutant and curli-producing E. coli enhance the disease phenotype in a hSOD1-G93A mouse model of ALS

The gut microbiome is a potential non-genetic contributing factor for Amyotrophic Lateral Sclerosis. Differences in gut microbial communities have been detected between ALS subjects and healthy controls, including an increase in Escherichia coli in ALS subjects. E. coli and other gram-negative bacte...

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Detalles Bibliográficos
Autores principales: Kurlawala, Zimple, McMillan, Joseph D., Singhal, Richa A., Morehouse, Johnny, Burke, Darlene A., Sears, Sophia M., Duregon, Eleonora, Beverly, Levi J., Siskind, Leah J., Friedland, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097672/
https://www.ncbi.nlm.nih.gov/pubmed/37045868
http://dx.doi.org/10.1038/s41598-023-32594-5

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