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Patient-derived xenograft models in cancer therapy: technologies and applications

Patient-derived xenograft (PDX) models, in which tumor tissues from patients are implanted into immunocompromised or humanized mice, have shown superiority in recapitulating the characteristics of cancer, such as the spatial structure of cancer and the intratumor heterogeneity of cancer. Moreover, P...

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Detalles Bibliográficos
Autores principales:	Liu, Yihan, Wu, Wantao, Cai, Changjing, Zhang, Hao, Shen, Hong, Han, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097874/ https://www.ncbi.nlm.nih.gov/pubmed/37045827 http://dx.doi.org/10.1038/s41392-023-01419-2

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