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LRPPRC facilitates tumor progression and immune evasion through upregulation of m(6)A modification of PD-L1 mRNA in hepatocellular carcinoma

OBJECTIVE: LRPPRC is a newly discovered N(6)-methyladenosine (m(6)A) modification reader, which potentially affects hepatocellular carcinoma (HCC) progression. PD-L1 in tumor cells is essential for tumor immune evasion. This work investigated the LRPPRC-mediated m(6)A-modification effect on PD-L1 mR...

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Detalles Bibliográficos
Autores principales:	Wang, Houhong, Tang, Amao, Cui, Yayun, Gong, Huihui, Li, Heng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097877/ https://www.ncbi.nlm.nih.gov/pubmed/37063837 http://dx.doi.org/10.3389/fimmu.2023.1144774

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