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Evaluating the effect of R-Baclofen and LP-211 on autistic behavior of the BTBR and Fmr1-KO mouse models

INTRODUCTION: Autism spectrum disorder (ASD) is a persistent neurodevelopmental condition characterized by two core behavioral symptoms: impaired social communication and interaction, as well as stereotypic, repetitive behavior. No distinct cause of ASD is known so far; however, excitatory/inhibitor...

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Detalles Bibliográficos
Autores principales: Sharghi, Shirin, Flunkert, Stefanie, Daurer, Magdalena, Rabl, Roland, Chagnaud, Boris Philippe, Leopoldo, Marcello, Lacivita, Enza, Hutter-Paier, Birgit, Prokesch, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097904/
https://www.ncbi.nlm.nih.gov/pubmed/37065917
http://dx.doi.org/10.3389/fnins.2023.1087788