Combined angiotensin-converting enzyme and aminopeptidase inhibition for treatment of experimental ventilator-induced lung injury in mice

Introduction: Ventilator-induced lung injury (VILI) may aggravate critical illness. Although angiotensin-converting enzyme (ACE) inhibition has beneficial effects in ventilator-induced lung injury, its clinical application is impeded by concomitant hypotension. We hypothesized that the aminopeptidas...

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Detalles Bibliográficos
Autores principales: Mao, Xinjun, Tretter, Verena, Zhu, Yi, Kraft, Felix, Vigl, Benjamin, Poglitsch, Marko, Ullrich, Roman, Abraham, Dietmar, Krenn, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097933/
https://www.ncbi.nlm.nih.gov/pubmed/37064885
http://dx.doi.org/10.3389/fphys.2023.1109452

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