4E-BP1 counteracts human mesenchymal stem cell senescence via maintaining mitochondrial homeostasis

Although the mTOR-4E-BP1 signaling pathway is implicated in aging and aging-related disorders, the role of 4E-BP1 in regulating human stem cell homeostasis remains largely unknown. Here, we report that the expression of 4E-BP1 decreases along with the senescence of human mesenchymal stem cells (hMSC...

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Detalles Bibliográficos
Autores principales: He, Yifang, Ji, Qianzhao, Wu, Zeming, Cai, Yusheng, Yin, Jian, Zhang, Yiyuan, Zhang, Sheng, Liu, Xiaoqian, Zhang, Weiqi, Liu, Guang-Hui, Wang, Si, Song, Moshi, Qu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098039/
https://www.ncbi.nlm.nih.gov/pubmed/36929036
http://dx.doi.org/10.1093/procel/pwac037

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