Uncovering the significance of expanded CD8(+) large granular lymphocytes in inclusion body myositis: Insights into T cell phenotype and functional alterations, and disease severity

INTRODUCTION: Inclusion body myositis (IBM) is a progressive inflammatory myopathy characterised by skeletal muscle infiltration and myofibre invasion by CD8(+) T lymphocytes. In some cases, IBM has been reported to be associated with a systemic lymphoproliferative disorder of CD8(+) T cells exhibit...

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Detalles Bibliográficos
Autores principales: McLeish, Emily, Sooda, Anuradha, Slater, Nataliya, Kachigunda, Barbara, Beer, Kelly, Paramalingam, Shereen, Lamont, Phillipa J., Chopra, Abha, Mastaglia, Frank Louis, Needham, Merrilee, Coudert, Jerome David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098158/
https://www.ncbi.nlm.nih.gov/pubmed/37063893
http://dx.doi.org/10.3389/fimmu.2023.1153789

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