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PRMT5 inhibition induces pro‐inflammatory macrophage polarization and increased hepatic triglyceride levels without affecting atherosclerosis in mice

Protein arginine methyltransferase 5 (PRMT5) controls inflammation and metabolism through modulation of histone methylation and gene transcription. Given the important role of inflammation and metabolism in atherosclerotic cardiovascular disease, here we examined the role of PRMT5 in atherosclerosis...

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Detalles Bibliográficos
Autores principales:	Zhang, Yiheng, Verwilligen, Robin A. F., Van Eck, Miranda, Hoekstra, Menno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098290/ https://www.ncbi.nlm.nih.gov/pubmed/36946061 http://dx.doi.org/10.1111/jcmm.17676

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