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Evaluation of Mycobacterium avium subsp. paratuberculosis isocitrate lyase (IcL) and ABC transporter (BacA) knockout mutants as vaccine candidates

There has been little success in controlling Johne’s disease, caused by Mycobacterium avium subsp. paratuberculosis, due to suboptimal diagnostics and the ineffectiveness of available vaccines. By knocking out BacA and IcL, genes required for MAP survival in dairy calves, two live-attenuated vaccine...

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Detalles Bibliográficos
Autores principales:	Eshraghisamani, Razieh, Arrazuria, Rakel, Luo, Lucy, De Buck, Jeroen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098363/ https://www.ncbi.nlm.nih.gov/pubmed/37065210 http://dx.doi.org/10.3389/fcimb.2023.1149419

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