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Peripheral nerve‐blocks and associations with length of stay and readmissions in fast‐track total hip and knee arthroplasty

BACKGROUND: Peripheral nerve blocks (PNB) have recently been recommended in total hip (THA) and knee (TKA) arthroplasty as they may reduce pain, morphine consumption, length of stay (LOS) and complications. However, whether PNBs are associated with early discharge within an enhanced recovery protoco...

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Autores principales: Jørgensen, Christoffer C., Petersen, Pelle B., Daugberg, Louise O., Jakobsen, Thomas, Gromov, Kirill, Varnum, Claus, Andersen, Mikkel R., Palm, Henrik, Kehlet, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098538/
https://www.ncbi.nlm.nih.gov/pubmed/36354132
http://dx.doi.org/10.1111/aas.14169
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author Jørgensen, Christoffer C.
Petersen, Pelle B.
Daugberg, Louise O.
Jakobsen, Thomas
Gromov, Kirill
Varnum, Claus
Andersen, Mikkel R.
Palm, Henrik
Kehlet, Henrik
author_facet Jørgensen, Christoffer C.
Petersen, Pelle B.
Daugberg, Louise O.
Jakobsen, Thomas
Gromov, Kirill
Varnum, Claus
Andersen, Mikkel R.
Palm, Henrik
Kehlet, Henrik
author_sort Jørgensen, Christoffer C.
collection PubMed
description BACKGROUND: Peripheral nerve blocks (PNB) have recently been recommended in total hip (THA) and knee (TKA) arthroplasty as they may reduce pain, morphine consumption, length of stay (LOS) and complications. However, whether PNBs are associated with early discharge within an enhanced recovery protocol including multimodal analgesia is uncertain. METHODS: An observational multicenter study from January to August 2017 in six Danish Arthroplasty Centers with established fast‐track protocols. Prospective recording of preoperative characteristics and information on PNB, LOS and readmissions through the Danish National Patient Registry and medical records. Multiple logistic regression was used to investigate associations between PNB and a LOS >1 day, LOS >4 days, and 30‐days readmissions. We also reported on mobilization, pain, opioid and fall‐related complications leading to LOS >4 days or readmissions. RESULTS: A total of 2027 (58.6%) THA and 1432 (41.4%) TKAs with a median LOS of 1 day (IQR 1–2) and 5.3% (CI:4.6–6.1) 30‐days readmission rate were identified. PNB was used in 40.7% (CI:38.2–43.3) of TKA and 2.7% (CI:2.0–3.5) of THA, but with considerable interdepartmental variation (0.0–89.0% for TKA). There was no association between PNB and LOS >1 day (OR:1.19 CI:0.82–1.72; p = .354), LOS >4 days (OR:1.4 CI:0.68–2.89; p = .359) or 30‐days readmissions (OR:1.02 CI:0.63–1.65; p = .935) in TKA. Logistic regression in THA was not possible due to limited use of PNB. In TKA there were 12 (2.1% CI:1.2–3.6) with and 1 (0.1% CI:0.02–0.7) without a PNB, who had mobilization, pain or opioid‐related complications, and 5 (0.9% CI:0.4–2.0) versus 4 (0.5% CI:0.2–1.2) who fell. Correspondingly, 2 (3.7% CI:1.0–12.6) and 11 (0.6% CI:0.3–1.0) of THA patients had these complications, while 0 (0.0% CI:0.0–6.6) and 17 (0.8% CI:0.5–1.3) fell. CONCLUSION: Routine use of peripheral nerve blocks was not associated with early discharge or 30‐days readmissions in fast‐track THA and TKA. Future studies should focus on benefits of PNB in high‐risk patients.
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spelling pubmed-100985382023-04-14 Peripheral nerve‐blocks and associations with length of stay and readmissions in fast‐track total hip and knee arthroplasty Jørgensen, Christoffer C. Petersen, Pelle B. Daugberg, Louise O. Jakobsen, Thomas Gromov, Kirill Varnum, Claus Andersen, Mikkel R. Palm, Henrik Kehlet, Henrik Acta Anaesthesiol Scand General Anaesthesia BACKGROUND: Peripheral nerve blocks (PNB) have recently been recommended in total hip (THA) and knee (TKA) arthroplasty as they may reduce pain, morphine consumption, length of stay (LOS) and complications. However, whether PNBs are associated with early discharge within an enhanced recovery protocol including multimodal analgesia is uncertain. METHODS: An observational multicenter study from January to August 2017 in six Danish Arthroplasty Centers with established fast‐track protocols. Prospective recording of preoperative characteristics and information on PNB, LOS and readmissions through the Danish National Patient Registry and medical records. Multiple logistic regression was used to investigate associations between PNB and a LOS >1 day, LOS >4 days, and 30‐days readmissions. We also reported on mobilization, pain, opioid and fall‐related complications leading to LOS >4 days or readmissions. RESULTS: A total of 2027 (58.6%) THA and 1432 (41.4%) TKAs with a median LOS of 1 day (IQR 1–2) and 5.3% (CI:4.6–6.1) 30‐days readmission rate were identified. PNB was used in 40.7% (CI:38.2–43.3) of TKA and 2.7% (CI:2.0–3.5) of THA, but with considerable interdepartmental variation (0.0–89.0% for TKA). There was no association between PNB and LOS >1 day (OR:1.19 CI:0.82–1.72; p = .354), LOS >4 days (OR:1.4 CI:0.68–2.89; p = .359) or 30‐days readmissions (OR:1.02 CI:0.63–1.65; p = .935) in TKA. Logistic regression in THA was not possible due to limited use of PNB. In TKA there were 12 (2.1% CI:1.2–3.6) with and 1 (0.1% CI:0.02–0.7) without a PNB, who had mobilization, pain or opioid‐related complications, and 5 (0.9% CI:0.4–2.0) versus 4 (0.5% CI:0.2–1.2) who fell. Correspondingly, 2 (3.7% CI:1.0–12.6) and 11 (0.6% CI:0.3–1.0) of THA patients had these complications, while 0 (0.0% CI:0.0–6.6) and 17 (0.8% CI:0.5–1.3) fell. CONCLUSION: Routine use of peripheral nerve blocks was not associated with early discharge or 30‐days readmissions in fast‐track THA and TKA. Future studies should focus on benefits of PNB in high‐risk patients. John Wiley and Sons Inc. 2022-11-28 2023-02 /pmc/articles/PMC10098538/ /pubmed/36354132 http://dx.doi.org/10.1111/aas.14169 Text en © 2022 The Authors. Acta Anaesthesiologica Scandinavica published by John Wiley & Sons Ltd on behalf of Acta Anaesthesiologica Scandinavica Foundation. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle General Anaesthesia
Jørgensen, Christoffer C.
Petersen, Pelle B.
Daugberg, Louise O.
Jakobsen, Thomas
Gromov, Kirill
Varnum, Claus
Andersen, Mikkel R.
Palm, Henrik
Kehlet, Henrik
Peripheral nerve‐blocks and associations with length of stay and readmissions in fast‐track total hip and knee arthroplasty
title Peripheral nerve‐blocks and associations with length of stay and readmissions in fast‐track total hip and knee arthroplasty
title_full Peripheral nerve‐blocks and associations with length of stay and readmissions in fast‐track total hip and knee arthroplasty
title_fullStr Peripheral nerve‐blocks and associations with length of stay and readmissions in fast‐track total hip and knee arthroplasty
title_full_unstemmed Peripheral nerve‐blocks and associations with length of stay and readmissions in fast‐track total hip and knee arthroplasty
title_short Peripheral nerve‐blocks and associations with length of stay and readmissions in fast‐track total hip and knee arthroplasty
title_sort peripheral nerve‐blocks and associations with length of stay and readmissions in fast‐track total hip and knee arthroplasty
topic General Anaesthesia
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098538/
https://www.ncbi.nlm.nih.gov/pubmed/36354132
http://dx.doi.org/10.1111/aas.14169
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