Electrochemical Palladium‐Catalyzed Oxidative Carbonylation‐Cyclization of Enallenols

Herein, we report an electrochemical oxidative palladium‐catalyzed carbonylation‐carbocyclization of enallenols to afford γ‐lactones and spirolactones, which proceeds with excellent chemoselectivity. Interestingly, electrocatalysis was found to have an accelerating effect on the rate of the tandem p...

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Detalles Bibliográficos
Autores principales: Zhang, Jianwei, Das, Biswanath, Verho, Oscar, Bäckvall, Jan‐E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098644/
https://www.ncbi.nlm.nih.gov/pubmed/36222322
http://dx.doi.org/10.1002/anie.202212131
Descripción
Sumario:Herein, we report an electrochemical oxidative palladium‐catalyzed carbonylation‐carbocyclization of enallenols to afford γ‐lactones and spirolactones, which proceeds with excellent chemoselectivity. Interestingly, electrocatalysis was found to have an accelerating effect on the rate of the tandem process, leading to a more efficient reaction than that under chemical redox conditions.

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