Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma

Melanoma is a heterogenous malignancy with an unpredictable clinical course. Most patients who present in the clinic are diagnosed with primary melanoma, yet large‐scale sequencing efforts have focused primarily on metastatic disease. In this study we sequence‐profiled 524 American Joint Committee o...

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Detalles Bibliográficos
Autores principales: Birkeälv, Sofia, Harland, Mark, Matsuyama, Larissa Satiko Alcantara Sekimoto, Rashid, Mamun, Mehta, Ishan, Laye, Jonathan P, Haase, Kerstin, Mell, Tracey, Iyer, Vivek, Robles‐Espinoza, Carla Daniela, McDermott, Ultan, van Loo, Peter, Kuijjer, Marieke L, Possik, Patricia A, Maria Engler, Silvya Stuchi, Bishop, D Timothy, Newton‐Bishop, Julia, Adams, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098817/
https://www.ncbi.nlm.nih.gov/pubmed/36219477
http://dx.doi.org/10.1002/path.6019

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