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Development of a Low-Frequency Piezoelectric Ultrasonic Transducer for Biological Tissue Sonication

The safety of ultrasound exposure is very important for a patient’s well-being. High-frequency (1–10 MHz) ultrasound waves are highly absorbed by biological tissue and have limited therapeutic effects on internal organs. This article presents the results of the development and application of a low-f...

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Autores principales: Ostasevicius, Vytautas, Jurenas, Vytautas, Mikuckyte, Sandra, Vezys, Joris, Stankevicius, Edgaras, Bubulis, Algimantas, Venslauskas, Mantas, Kizauskiene, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098853/
https://www.ncbi.nlm.nih.gov/pubmed/37050668
http://dx.doi.org/10.3390/s23073608
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author Ostasevicius, Vytautas
Jurenas, Vytautas
Mikuckyte, Sandra
Vezys, Joris
Stankevicius, Edgaras
Bubulis, Algimantas
Venslauskas, Mantas
Kizauskiene, Laura
author_facet Ostasevicius, Vytautas
Jurenas, Vytautas
Mikuckyte, Sandra
Vezys, Joris
Stankevicius, Edgaras
Bubulis, Algimantas
Venslauskas, Mantas
Kizauskiene, Laura
author_sort Ostasevicius, Vytautas
collection PubMed
description The safety of ultrasound exposure is very important for a patient’s well-being. High-frequency (1–10 MHz) ultrasound waves are highly absorbed by biological tissue and have limited therapeutic effects on internal organs. This article presents the results of the development and application of a low-frequency (20–100 kHz) ultrasonic transducer for sonication of biological tissues. Using the methodology of digital twins, consisting of virtual and physical twins, an ultrasonic transducer has been developed that emits a focused ultrasound signal that penetrates into deeper biological tissues. For this purpose, the ring-shaped end surface of this transducer is excited not only by the main longitudinal vibrational mode, which is typical of the flat end surface transducers used to date, but also by higher mode radial vibrations. The virtual twin simulation shows that the acoustic signal emitted by the ring-shaped transducer, which is excited by a higher vibrational mode, is concentrated into a narrower and more precise acoustic wave that penetrates deeper into the biological tissue and affects only the part of the body to be treated, but not the whole body.
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spelling pubmed-100988532023-04-14 Development of a Low-Frequency Piezoelectric Ultrasonic Transducer for Biological Tissue Sonication Ostasevicius, Vytautas Jurenas, Vytautas Mikuckyte, Sandra Vezys, Joris Stankevicius, Edgaras Bubulis, Algimantas Venslauskas, Mantas Kizauskiene, Laura Sensors (Basel) Article The safety of ultrasound exposure is very important for a patient’s well-being. High-frequency (1–10 MHz) ultrasound waves are highly absorbed by biological tissue and have limited therapeutic effects on internal organs. This article presents the results of the development and application of a low-frequency (20–100 kHz) ultrasonic transducer for sonication of biological tissues. Using the methodology of digital twins, consisting of virtual and physical twins, an ultrasonic transducer has been developed that emits a focused ultrasound signal that penetrates into deeper biological tissues. For this purpose, the ring-shaped end surface of this transducer is excited not only by the main longitudinal vibrational mode, which is typical of the flat end surface transducers used to date, but also by higher mode radial vibrations. The virtual twin simulation shows that the acoustic signal emitted by the ring-shaped transducer, which is excited by a higher vibrational mode, is concentrated into a narrower and more precise acoustic wave that penetrates deeper into the biological tissue and affects only the part of the body to be treated, but not the whole body. MDPI 2023-03-30 /pmc/articles/PMC10098853/ /pubmed/37050668 http://dx.doi.org/10.3390/s23073608 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ostasevicius, Vytautas
Jurenas, Vytautas
Mikuckyte, Sandra
Vezys, Joris
Stankevicius, Edgaras
Bubulis, Algimantas
Venslauskas, Mantas
Kizauskiene, Laura
Development of a Low-Frequency Piezoelectric Ultrasonic Transducer for Biological Tissue Sonication
title Development of a Low-Frequency Piezoelectric Ultrasonic Transducer for Biological Tissue Sonication
title_full Development of a Low-Frequency Piezoelectric Ultrasonic Transducer for Biological Tissue Sonication
title_fullStr Development of a Low-Frequency Piezoelectric Ultrasonic Transducer for Biological Tissue Sonication
title_full_unstemmed Development of a Low-Frequency Piezoelectric Ultrasonic Transducer for Biological Tissue Sonication
title_short Development of a Low-Frequency Piezoelectric Ultrasonic Transducer for Biological Tissue Sonication
title_sort development of a low-frequency piezoelectric ultrasonic transducer for biological tissue sonication
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098853/
https://www.ncbi.nlm.nih.gov/pubmed/37050668
http://dx.doi.org/10.3390/s23073608
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