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Fangchinoline Exerts Anticancer Effects on Colorectal Cancer Cells by Evoking Cell Apoptosis via Endoplasmic Reticulum Stress

We studied the anti-tumor effect of fangchinoline (FAN) against human colorectal cancer cell lines CCL-244 and SW480 and analyzed the mechanism of FAN action. The cell viability and apoptosis were assessed by MTT test and Annexin V-PI staining; caspase-3 activity was measured by Western blotting. Th...

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Detalles Bibliográficos
Autores principales: Jiang, Xiuling, Hu, Yougen, Peng, Jianming, Luo, Xue, Su, Landi, Tang, Yuanjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098992/
https://www.ncbi.nlm.nih.gov/pubmed/37052856
http://dx.doi.org/10.1007/s10517-023-05761-x

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