Cargando…
G‐type Halohydrin Dehalogenases Catalyze Ring Opening Reactions of Cyclic Epoxides with Diverse Anionic Nucleophiles
Halohydrin dehalogenases are promiscuous biocatalysts, which enable asymmetric ring opening reactions of epoxides with various anionic nucleophiles. However, despite the increasing interest in such asymmetric transformations, the substrate scope of G‐type halohydrin dehalogenases toward cyclic epoxi...
Autores principales: | Solarczek, Jennifer, Kaspar, Felix, Bauer, Pia, Schallmey, Anett |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099379/ https://www.ncbi.nlm.nih.gov/pubmed/36214160 http://dx.doi.org/10.1002/chem.202202343 |
Ejemplares similares
-
Position 123 of halohydrin dehalogenase HheG plays an important role in stability, activity, and enantioselectivity
por: Solarczek, Jennifer, et al.
Publicado: (2019) -
Recent advances on halohydrin dehalogenases—from enzyme identification to novel biocatalytic applications
por: Schallmey, Anett, et al.
Publicado: (2016) -
Highly α-position regioselective ring-opening of epoxides catalyzed by halohydrin dehalogenase from Ilumatobacter coccineus: a biocatalytic approach to 2-azido-2-aryl-1-ols
por: An, Miao, et al.
Publicado: (2019) -
Enhancing the biocatalytic manufacture of the key intermediate of atorvastatin by focused directed evolution of halohydrin dehalogenase
por: Luo, Yu, et al.
Publicado: (2017) -
Switching the reaction pathways of electrochemically generated β-haloalkoxysulfonium ions – synthesis of halohydrins and epoxides
por: Shimizu, Akihiro, et al.
Publicado: (2015)