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Acute Pneumonia Like Illness and Sepsis in India: Is it Time to Suspect Pulmonary Melioidosis?

This article describes a case of melioidosis, a severe and potentially fatal disease caused by the Gram-negative bacillus Burkholderia pseudomallei, in a 55-year-old female in India. The disease is endemic in Southeast Asia and Northern Australia. Recently there has been an increased number of cases...

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Autores principales: Sampath, Ananyan, Sukumar, M, Tejaswini, Penuboina, Gupta, Ayush, Khadanga, Sagar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099402/
https://www.ncbi.nlm.nih.gov/pubmed/37065362
http://dx.doi.org/10.7759/cureus.36122
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author Sampath, Ananyan
Sukumar, M
Tejaswini, Penuboina
Gupta, Ayush
Khadanga, Sagar
author_facet Sampath, Ananyan
Sukumar, M
Tejaswini, Penuboina
Gupta, Ayush
Khadanga, Sagar
author_sort Sampath, Ananyan
collection PubMed
description This article describes a case of melioidosis, a severe and potentially fatal disease caused by the Gram-negative bacillus Burkholderia pseudomallei, in a 55-year-old female in India. The disease is endemic in Southeast Asia and Northern Australia. Recently there has been an increased number of cases reported in India. The source of B. pseudomallei in India is thought to be soil and water, with the most common mode of infection being through skin contact. The clinical presentation of melioidosis in India varies greatly, making diagnosis difficult. The case presented here with a history of acute febrile illness and progressive dyspnoea, with clinical worsening leading to intensive care unit (ICU) care. We managed this acute pneumonia-like melioidosis with antibiotics and supportive care which showed rapid recovery at follow-up. This case highlights the need for a high index of suspicion and increased awareness of early diagnosis of melioidosis in the Indian subcontinent to improve the patient.
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spelling pubmed-100994022023-04-14 Acute Pneumonia Like Illness and Sepsis in India: Is it Time to Suspect Pulmonary Melioidosis? Sampath, Ananyan Sukumar, M Tejaswini, Penuboina Gupta, Ayush Khadanga, Sagar Cureus Internal Medicine This article describes a case of melioidosis, a severe and potentially fatal disease caused by the Gram-negative bacillus Burkholderia pseudomallei, in a 55-year-old female in India. The disease is endemic in Southeast Asia and Northern Australia. Recently there has been an increased number of cases reported in India. The source of B. pseudomallei in India is thought to be soil and water, with the most common mode of infection being through skin contact. The clinical presentation of melioidosis in India varies greatly, making diagnosis difficult. The case presented here with a history of acute febrile illness and progressive dyspnoea, with clinical worsening leading to intensive care unit (ICU) care. We managed this acute pneumonia-like melioidosis with antibiotics and supportive care which showed rapid recovery at follow-up. This case highlights the need for a high index of suspicion and increased awareness of early diagnosis of melioidosis in the Indian subcontinent to improve the patient. Cureus 2023-03-14 /pmc/articles/PMC10099402/ /pubmed/37065362 http://dx.doi.org/10.7759/cureus.36122 Text en Copyright © 2023, Sampath et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Sampath, Ananyan
Sukumar, M
Tejaswini, Penuboina
Gupta, Ayush
Khadanga, Sagar
Acute Pneumonia Like Illness and Sepsis in India: Is it Time to Suspect Pulmonary Melioidosis?
title Acute Pneumonia Like Illness and Sepsis in India: Is it Time to Suspect Pulmonary Melioidosis?
title_full Acute Pneumonia Like Illness and Sepsis in India: Is it Time to Suspect Pulmonary Melioidosis?
title_fullStr Acute Pneumonia Like Illness and Sepsis in India: Is it Time to Suspect Pulmonary Melioidosis?
title_full_unstemmed Acute Pneumonia Like Illness and Sepsis in India: Is it Time to Suspect Pulmonary Melioidosis?
title_short Acute Pneumonia Like Illness and Sepsis in India: Is it Time to Suspect Pulmonary Melioidosis?
title_sort acute pneumonia like illness and sepsis in india: is it time to suspect pulmonary melioidosis?
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099402/
https://www.ncbi.nlm.nih.gov/pubmed/37065362
http://dx.doi.org/10.7759/cureus.36122
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