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Dithiolopyrrolones are Prochelators that are Activated by Glutathione
Dithiolopyrrolones (DTPs), such as holomycin, are natural products that hold promise as scaffolds for antibiotics as they exhibit inhibitory activity against antibiotic‐resistant pathogens. They consist of a unique bicyclic core containing a disulfide that is crucial for their biological activity. H...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099403/ https://www.ncbi.nlm.nih.gov/pubmed/36214647 http://dx.doi.org/10.1002/chem.202202567 |