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Disseminated Cryptococcosis Following Eculizumab Therapy: Insight Into Pathogenesis

Eculizumab, a recombinant humanized monoclonal antibody (mAb), is used for the treatment of patients (both adults and children) with paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome. This mAb binds to complement protein 5 (C5), thereby inhibiting its cleavage. On the other...

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Detalles Bibliográficos
Autores principales: Lortholary, Olivier, El-Sissy, Carine, Leporrier, Jérémie, Sze Wah Wong, Sarah, Dannaoui, Eric, Fremeaux-Bacchi, Véronique, Aimanianda, Vishukumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099467/
https://www.ncbi.nlm.nih.gov/pubmed/37065989
http://dx.doi.org/10.1093/ofid/ofad159