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Efzofitimod: a novel anti-inflammatory agent for sarcoidosis

Efzofitimod is a first-in-class biologic immunomodulator based on a naturally occurring splice variant of histidyl-tRNA synthetase (HARS) that binds to neuropilin-2 (NRP2). Preclinical data found high expression of NRP2 in sarcoidosis granulomas. Treatment with efzofitimod reduced the granulomatous...

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Detalles Bibliográficos
Autores principales:	Baughman, Robert P., Niranjan, Vis, Walker, Gennyne, Burkart, Christoph, Paz, Suzanne, Chong, Yeeting E., Siefker, David, Sun, Eileen, Nangle, Leslie, Förster, Sarah, Muders, Michael H., Farver, Carol F., Lower, Elyse E., Shukla, Sanjay, Culver, Daniel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mattioli 1885 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099656/ https://www.ncbi.nlm.nih.gov/pubmed/36975051 http://dx.doi.org/10.36141/svdld.v40i1.14396

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