Cytoplasmic HDAC4 recovers synaptic function in the 3×Tg mouse model of Alzheimer's disease

AIMS: Early dysfunction in Alzheimer's disease (AD) is characterised by alterations of synapse structure and function leading to dysmorphic neurites, decreased spine density, impaired synaptic plasticity and cognitive deficits. The class II member HDAC4, which recently emerged as a crucial fact...

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Detalles Bibliográficos
Autores principales: Colussi, Claudia, Aceto, Giuseppe, Ripoli, Cristian, Bertozzi, Alessia, Li Puma, Domenica Donatella, Paccosi, Elena, D'Ascenzo, Marcello, Grassi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099707/
https://www.ncbi.nlm.nih.gov/pubmed/36331820
http://dx.doi.org/10.1111/nan.12861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099707/
https://www.ncbi.nlm.nih.gov/pubmed/36331820
http://dx.doi.org/10.1111/nan.12861

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