LncRNA AC006064.4–201 serves as a novel molecular marker in alleviating cartilage senescence and protecting against osteoarthritis by destabilizing CDKN1B mRNA via interacting with PTBP1

BACKGROUND: Osteoarthritis (OA) is the most prevalent age-related disease in the world. Chondrocytes undergo an age-dependent decline in their proliferation and synthetic capacity, which is the main cause of OA development. However, the intrinsic mechanism of chondrocyte senescence is still unclear....

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Detalles Bibliográficos
Autores principales: Shen, Panyang, Gao, Jun, Huang, Shaohan, You, Chenan, Wang, Haitao, Chen, Pengyu, Yao, Teng, Gao, Tianyou, Zhou, Bohao, Shen, Shuying, Zhao, Xing, Ma, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099822/
https://www.ncbi.nlm.nih.gov/pubmed/37055817
http://dx.doi.org/10.1186/s40364-023-00477-6

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