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Site‐directed mutagenesis of HLA molecules reveals the functional epitope of a human HLA‐A1/A36‐specific monoclonal antibody

Eplet 44KM is currently listed in the HLA Epitope Registry but does not adhere to the eplet definition of an amino acid configuration within a 3.5 Å radius. Eplet 44KM has been previously redefined to the antibody‐verified reactivity pattern 44K/150V/158V, based on reactivity analysis of monoclonal...

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Detalles Bibliográficos
Autores principales: Meng, Tina, Bezstarosti, Suzanne, Singh, Ujjwala, Yap, Michelle, Scott, Laura, Petrosyan, Naiiry, Quiroz, Fred, Eps, Ned Van, Hui, Eric Ka‐Wai, Suh, David, Zhu, Quansheng, Pei, Rui, Kramer, Cynthia S. M., Claas, Frans H. J., Lowe, David, Heidt, Sebastiaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099858/
https://www.ncbi.nlm.nih.gov/pubmed/36401817
http://dx.doi.org/10.1111/tan.14895

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