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Impact of Peptide Sequences on Their Structure and Function: Mimicking of Virus‐Like Nanoparticles for Nucleic Acid Delivery

We rationally designed a series of amphiphilic hepta‐peptides enriched with a chemically conjugated guanidiniocarbonylpyrrole (GCP) unit at the lysine side chain. All peptides are composed of polar (GCP) and non‐polar (cyclohexyl alanine) residues but differ in their sequence periodicity, resulting...

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Detalles Bibliográficos
Autores principales: Jana, Poulami, Samanta, Krishnananda, Ehlers, Martin, Zellermann, Elio, Bäcker, Sandra, Stauber, Roland H., Schmuck, Carsten, Knauer, Shirley K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10099937/
https://www.ncbi.nlm.nih.gov/pubmed/36314419
http://dx.doi.org/10.1002/cbic.202200519