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Preserving the pulmonary valve in Tetralogy of Fallot repair: Reconsidering the indication for valve‐sparing

BACKGROUND: Tetralogy of Fallot (TOF) repair is a frequent procedure, and although valve‐sparing (VS) repair is preferred, determining which patients can successfully undergo this operation remains controversial. We sought to identify parameters to determine a selective, accurate indication for VS r...

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Autores principales: Siddiqi, Umar, Adewale, Adedotun, Pena, Emily, Schulz, Kelci, Ilbawi, Michel, El‐Zein, Chawki, Vricella, Luca, Hibino, Narutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100041/
https://www.ncbi.nlm.nih.gov/pubmed/36378940
http://dx.doi.org/10.1111/jocs.17156
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author Siddiqi, Umar
Adewale, Adedotun
Pena, Emily
Schulz, Kelci
Ilbawi, Michel
El‐Zein, Chawki
Vricella, Luca
Hibino, Narutoshi
author_facet Siddiqi, Umar
Adewale, Adedotun
Pena, Emily
Schulz, Kelci
Ilbawi, Michel
El‐Zein, Chawki
Vricella, Luca
Hibino, Narutoshi
author_sort Siddiqi, Umar
collection PubMed
description BACKGROUND: Tetralogy of Fallot (TOF) repair is a frequent procedure, and although valve‐sparing (VS) repair is preferred, determining which patients can successfully undergo this operation remains controversial. We sought to identify parameters to determine a selective, accurate indication for VS repair. METHODS: We reviewed 71 patients (82%) undergoing VS repair. We analyzed hemodynamic data, intraoperative reports, and follow‐up echocardiography results to identify acceptable indications. Patients requiring pulmonary valve (PV) reintervention versus no reintervention were compared. RESULTS: PV annulus size at repair was z‐score of −2.0 (−5.3, 1.3). Approximately half (51%) had a z‐score less than −2. Cox regression results showed this was not a risk factor for reintervention (p = .59). Overall, 1‐, 3‐, 5‐, and 10‐year freedom from PV reintervention rates were 95.8%, 92.8%, 91% and 77.8%, respectively. Residual pulmonary stenosis (PS) at initial repair was relatively higher in the reintervention group compared with no reintervention group (40 [28, 51] mmHg vs. 30 [22, 37] mmHg; p = .08). For patients with residual PS, pressure gradient (PG) was consistent over time across both groups (PV reintervention: −3 [−15, 8] mmHg vs. no reintervention: 0 [−9, 8] mmHg). The risk of PV reintervention is 3.7‐fold higher when the PG from intraoperative TEE is greater than 45 mmHg (p = .04). CONCLUSIONS: Our review of the midterm outcomes of expanded indication for VS suggests intraoperative decision to convert to transannular patch is warranted if intraoperative postprocedure TEE PG is greater than 45 mmHg or RV pressure is higher than half of systemic pressure to prevent reintervention.
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spelling pubmed-101000412023-04-14 Preserving the pulmonary valve in Tetralogy of Fallot repair: Reconsidering the indication for valve‐sparing Siddiqi, Umar Adewale, Adedotun Pena, Emily Schulz, Kelci Ilbawi, Michel El‐Zein, Chawki Vricella, Luca Hibino, Narutoshi J Card Surg Regular Issue Papers BACKGROUND: Tetralogy of Fallot (TOF) repair is a frequent procedure, and although valve‐sparing (VS) repair is preferred, determining which patients can successfully undergo this operation remains controversial. We sought to identify parameters to determine a selective, accurate indication for VS repair. METHODS: We reviewed 71 patients (82%) undergoing VS repair. We analyzed hemodynamic data, intraoperative reports, and follow‐up echocardiography results to identify acceptable indications. Patients requiring pulmonary valve (PV) reintervention versus no reintervention were compared. RESULTS: PV annulus size at repair was z‐score of −2.0 (−5.3, 1.3). Approximately half (51%) had a z‐score less than −2. Cox regression results showed this was not a risk factor for reintervention (p = .59). Overall, 1‐, 3‐, 5‐, and 10‐year freedom from PV reintervention rates were 95.8%, 92.8%, 91% and 77.8%, respectively. Residual pulmonary stenosis (PS) at initial repair was relatively higher in the reintervention group compared with no reintervention group (40 [28, 51] mmHg vs. 30 [22, 37] mmHg; p = .08). For patients with residual PS, pressure gradient (PG) was consistent over time across both groups (PV reintervention: −3 [−15, 8] mmHg vs. no reintervention: 0 [−9, 8] mmHg). The risk of PV reintervention is 3.7‐fold higher when the PG from intraoperative TEE is greater than 45 mmHg (p = .04). CONCLUSIONS: Our review of the midterm outcomes of expanded indication for VS suggests intraoperative decision to convert to transannular patch is warranted if intraoperative postprocedure TEE PG is greater than 45 mmHg or RV pressure is higher than half of systemic pressure to prevent reintervention. John Wiley and Sons Inc. 2022-11-15 2022-12 /pmc/articles/PMC10100041/ /pubmed/36378940 http://dx.doi.org/10.1111/jocs.17156 Text en © 2022 The Authors. Journal of Cardiac Surgery published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Regular Issue Papers
Siddiqi, Umar
Adewale, Adedotun
Pena, Emily
Schulz, Kelci
Ilbawi, Michel
El‐Zein, Chawki
Vricella, Luca
Hibino, Narutoshi
Preserving the pulmonary valve in Tetralogy of Fallot repair: Reconsidering the indication for valve‐sparing
title Preserving the pulmonary valve in Tetralogy of Fallot repair: Reconsidering the indication for valve‐sparing
title_full Preserving the pulmonary valve in Tetralogy of Fallot repair: Reconsidering the indication for valve‐sparing
title_fullStr Preserving the pulmonary valve in Tetralogy of Fallot repair: Reconsidering the indication for valve‐sparing
title_full_unstemmed Preserving the pulmonary valve in Tetralogy of Fallot repair: Reconsidering the indication for valve‐sparing
title_short Preserving the pulmonary valve in Tetralogy of Fallot repair: Reconsidering the indication for valve‐sparing
title_sort preserving the pulmonary valve in tetralogy of fallot repair: reconsidering the indication for valve‐sparing
topic Regular Issue Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100041/
https://www.ncbi.nlm.nih.gov/pubmed/36378940
http://dx.doi.org/10.1111/jocs.17156
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