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The hypertension and hyperlipidemia status among type 2 diabetic patients in the community and influencing factors analysis of glycemic control

OBJECTIVE: To understand the prevalence of hypertension and hyperlipidaemia as well as the current status of glycaemic control and its influencing factors among type 2 diabetes mellitus patients in the community in South China, and to provide recommendations for the prevention and control of diabete...

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Autores principales: Zhai, Zhiyu, Yang, Yunou, Lin, Guozhen, Lin, Weiquan, Wu, Jiagang, Liu, Xiangyi, Zhang, Shijia, Zhou, Qin, Liu, Hui, Hao, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100166/
https://www.ncbi.nlm.nih.gov/pubmed/37046317
http://dx.doi.org/10.1186/s13098-023-01013-0
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author Zhai, Zhiyu
Yang, Yunou
Lin, Guozhen
Lin, Weiquan
Wu, Jiagang
Liu, Xiangyi
Zhang, Shijia
Zhou, Qin
Liu, Hui
Hao, Guang
author_facet Zhai, Zhiyu
Yang, Yunou
Lin, Guozhen
Lin, Weiquan
Wu, Jiagang
Liu, Xiangyi
Zhang, Shijia
Zhou, Qin
Liu, Hui
Hao, Guang
author_sort Zhai, Zhiyu
collection PubMed
description OBJECTIVE: To understand the prevalence of hypertension and hyperlipidaemia as well as the current status of glycaemic control and its influencing factors among type 2 diabetes mellitus patients in the community in South China, and to provide recommendations for the prevention and control of diabetes. METHODS: Questionnaires, physical examinations and laboratory tests were conducted on patients with type 2 diabetes mellitus who participated in the National Basic Public Health Service Programme in Guangzhou in 2020. The chi-square test, t-test and multi-factor unconditional logistic regression analysis were performed using R 4.1.2 software. RESULT: Among 127,423 type 2 diabetic patients in Guangzhou, 57,695 achieved glycemic control standards, with a glycemic control rate of 45.28%.In this study, the proportion of T2DM patients with hypertension and hyperlipidaemia together was 27.79%, The percentage of T2DM patients with hypertension alone and hyperlipidaemia alone was 28.34% and 20.53% respectively, and the rate of no complications was 23.34%. There was a statistically significant difference in the rate of glycaemic control between the different disease combination states (P < 0.05). The glycaemic control rate was 47.67% in diabetic patients without hypertension and hyperlipidaemia, 52.54% and 37.24% in those with combined hypertension alone and hyperlipidaemia alone respectively, compared to 41.80% in diabetic patients with hypertension and hyperlipidaemia. After adjusting for all covariates, multivariate analysis showed that combined hypertension alone was associated with good glycaemic control (OR 0.817, 95% CI 0.791, 0.843, P < 0.001),when using comorbid T2DM as a control group, combined hyperlipidaemia alone, combined hypertension and hyperlipidaemia were associated with poor glycaemic control (OR 1.521, 95% CI 1.470,1.574, P < 0.001 and OR 1.250, 95% CI 1.211,1.291, P < 0.001), Subgroup analyses as well as multifactorial unconditional logistic regression analyses showed that patients with type 2 diabetes who were overweight and obese, smoked, drank alcohol, had a diagnosis of diabetes for ≥ 6 years, had fair or poor adherence and had a family history of diabetes had lower rates of glycaemic control. CONCLUSION: The results of this study showed that the co-morbidity of hypertension and hyperlipidaemia was high and prevalent among diabetic patients in Guangzhou. Moreover, glycaemic control of T2DM patients with hyperlipidaemia was lower than other diabetic patients. Obesity and overweight, poor lifestyle and dietary habits are also major factors affecting the treatment and control of T2D patients in this region. Therefore, comprehensive measures should be actively taken to control blood glucose levels in type 2 diabetic patients by also incorporating lipid management into the community and strictly controlling lipid levels. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13098-023-01013-0.
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spelling pubmed-101001662023-04-14 The hypertension and hyperlipidemia status among type 2 diabetic patients in the community and influencing factors analysis of glycemic control Zhai, Zhiyu Yang, Yunou Lin, Guozhen Lin, Weiquan Wu, Jiagang Liu, Xiangyi Zhang, Shijia Zhou, Qin Liu, Hui Hao, Guang Diabetol Metab Syndr Research OBJECTIVE: To understand the prevalence of hypertension and hyperlipidaemia as well as the current status of glycaemic control and its influencing factors among type 2 diabetes mellitus patients in the community in South China, and to provide recommendations for the prevention and control of diabetes. METHODS: Questionnaires, physical examinations and laboratory tests were conducted on patients with type 2 diabetes mellitus who participated in the National Basic Public Health Service Programme in Guangzhou in 2020. The chi-square test, t-test and multi-factor unconditional logistic regression analysis were performed using R 4.1.2 software. RESULT: Among 127,423 type 2 diabetic patients in Guangzhou, 57,695 achieved glycemic control standards, with a glycemic control rate of 45.28%.In this study, the proportion of T2DM patients with hypertension and hyperlipidaemia together was 27.79%, The percentage of T2DM patients with hypertension alone and hyperlipidaemia alone was 28.34% and 20.53% respectively, and the rate of no complications was 23.34%. There was a statistically significant difference in the rate of glycaemic control between the different disease combination states (P < 0.05). The glycaemic control rate was 47.67% in diabetic patients without hypertension and hyperlipidaemia, 52.54% and 37.24% in those with combined hypertension alone and hyperlipidaemia alone respectively, compared to 41.80% in diabetic patients with hypertension and hyperlipidaemia. After adjusting for all covariates, multivariate analysis showed that combined hypertension alone was associated with good glycaemic control (OR 0.817, 95% CI 0.791, 0.843, P < 0.001),when using comorbid T2DM as a control group, combined hyperlipidaemia alone, combined hypertension and hyperlipidaemia were associated with poor glycaemic control (OR 1.521, 95% CI 1.470,1.574, P < 0.001 and OR 1.250, 95% CI 1.211,1.291, P < 0.001), Subgroup analyses as well as multifactorial unconditional logistic regression analyses showed that patients with type 2 diabetes who were overweight and obese, smoked, drank alcohol, had a diagnosis of diabetes for ≥ 6 years, had fair or poor adherence and had a family history of diabetes had lower rates of glycaemic control. CONCLUSION: The results of this study showed that the co-morbidity of hypertension and hyperlipidaemia was high and prevalent among diabetic patients in Guangzhou. Moreover, glycaemic control of T2DM patients with hyperlipidaemia was lower than other diabetic patients. Obesity and overweight, poor lifestyle and dietary habits are also major factors affecting the treatment and control of T2D patients in this region. Therefore, comprehensive measures should be actively taken to control blood glucose levels in type 2 diabetic patients by also incorporating lipid management into the community and strictly controlling lipid levels. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13098-023-01013-0. BioMed Central 2023-04-13 /pmc/articles/PMC10100166/ /pubmed/37046317 http://dx.doi.org/10.1186/s13098-023-01013-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Zhai, Zhiyu
Yang, Yunou
Lin, Guozhen
Lin, Weiquan
Wu, Jiagang
Liu, Xiangyi
Zhang, Shijia
Zhou, Qin
Liu, Hui
Hao, Guang
The hypertension and hyperlipidemia status among type 2 diabetic patients in the community and influencing factors analysis of glycemic control
title The hypertension and hyperlipidemia status among type 2 diabetic patients in the community and influencing factors analysis of glycemic control
title_full The hypertension and hyperlipidemia status among type 2 diabetic patients in the community and influencing factors analysis of glycemic control
title_fullStr The hypertension and hyperlipidemia status among type 2 diabetic patients in the community and influencing factors analysis of glycemic control
title_full_unstemmed The hypertension and hyperlipidemia status among type 2 diabetic patients in the community and influencing factors analysis of glycemic control
title_short The hypertension and hyperlipidemia status among type 2 diabetic patients in the community and influencing factors analysis of glycemic control
title_sort hypertension and hyperlipidemia status among type 2 diabetic patients in the community and influencing factors analysis of glycemic control
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100166/
https://www.ncbi.nlm.nih.gov/pubmed/37046317
http://dx.doi.org/10.1186/s13098-023-01013-0
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