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Synthesis of a Bifunctional Cross‐Bridged Chelating Agent, Peptide Conjugation, and Comparison of (68)Ga Labeling and Complex Stability Characteristics with Established Chelators

[(68)Ga]Ga(3+) can be introduced into receptor‐specific peptidic carriers via different chelators to obtain radiotracers for Positron Emission Tomography imaging and the chosen chelating agent considerably influences the in vivo pharmacokinetics of the corresponding radiopeptides. A chelator that sh...

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Detalles Bibliográficos
Autores principales: Damerow, Helen, Wängler, Björn, Schirrmacher, Ralf, Fricker, Gert, Wängler, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10100262/
https://www.ncbi.nlm.nih.gov/pubmed/36259364
http://dx.doi.org/10.1002/cmdc.202200495